Weefsel Pharma - A Globally Top Rated Diphenhydramine Manufacturer and Exporter in India     

Each one of us at Weefsel Pharma, run on the sole intension of manufacturing and supplying the world with a vast range of core and allied healthcare products, that symbolize the finest world-class standards; falling under multiple categories

It is just an added bonus for us that our indomitable strong intension, is not only offering us a sense of optimum satisfaction but also successfully generating record high sales in this highly competitive world of pharmaceuticals. We take extreme pride to have been able to get a strong foothold while establishing a stable market, that spans over more than fifty countries, for our products and services

The portfolio that we are currently maintaining, include a wide range of pharma products. We are proudly delivering these to numerous nations across the globe. It should be noted here that we have included both branded as well as generic medicines in our product portfolio, having exclusive segments for both human healthcare as well as veterinary medicines. 

Among the medicines that we are exporting worldwide, Diphenhydramine is a pharmaceutical drug that has seen much demand. We as a globally reputed Diphenhydramine manufacturer and exporter in India, are maintaining world-class standards in each of our production units.


Combinations of Diphenhydramine Manufactured by Weefsel Pharma 

  • Paracetamol + Phenylephrine + Caffeine + Diphenhydramine
  • Paracetamol IP + Phenylephrine IP + Caffeine IP + Diphenhydramine IP


Dosage forms of Diphenhydramine Manufactured by Weefsel Pharma 

Products :

Product/Composition Strength View
Paracetamol, Phenylephrine, Caffeine and Diphenhydramine Tablets 500mg + 5mg + 30mg + 25mg View
Flusel Cold Tablets 500mg + 5mg + 30mg + 25mg View
Diphenhydramine, Ammonium Chloride and Sodium Citrate Syrup 14.08mg/5ml + 138mg/5ml + 57.03mg/5ml View

What is Diphenhydramine?   

Diphenhydramine is a first-generation antihistamine H1 receptor and anti-allergic that is used in the treatment of seasonal allergies, and various allergic reactions.  


How does Diphenhydramine work? 

Diphenhydramine predominantly works via the antagonism of H1 (Histamine 1) receptors, located on respiratory smooth muscles, vascular endothelial cells, the gastrointestinal tract (GIT), cardiac tissue, immune cells, the uterus, and the central nervous system (CNS) neurons, etc. 

When the H1 receptor is stimulated, it produces multiple reactions; including increased vascular permeability, promotion of vasodilation causing flushing, decreased atrioventricular (AV) node conduction time, stimulation of sensory nerves of airways producing coughing, smooth muscle contraction of bronchi and the GIT and eosinophilic chemotaxis that promotes the allergic immune response. 

Finally it acts as an inverse agonist at the H1 receptors, and eventually reverses effects of histamine on capillaries, so as to reduce the allergic reaction symptoms. Moreover it readily crosses the blood-brain barrier and inversely agonizes the H1 CNS receptors, resulting in drowsiness, and suppressing the medullary cough center. 


Popular Treatments or Diseases and Health Issues associated with Diphenhydramine 

  • Allergic Reaction
  • Allergic Rhinitis (AR)
  • Allergic cough
  • Allergy to Tree Pollen
  • Anaphylaxis
  • Angioedema
  • Common Cold
  • Conjunctival irritation
  • Cough
  • Cough Variant Asthma
  • Cough caused by Common Cold
  • Eye allergy
  • Fever
  • Insect Bites
  • Insect Stings
  • Insomnia
  • Irritative cough
  • Itching of the nose
  • Itching of the throat
  • Motion Sickness
  • Nasal Congestion
  • Oral Mucositis
  • Pain
  • Parkinsonian Syndromes
  • Productive cough
  • Pruritus
  • Rashes
  • Rhinorrhoea
  • Sinus Congestion
  • Sinus headache
  • Skin Irritation
  • Sneezing
  • Sunburn
  • Symptoms of Acute Bronchitis Accompanied by Coughing
  • Upper respiratory tract hypersensitivity reaction, site unspecified
  • Urticaria
  • Cold or flu syndrome
  • Dermatographism
  • Dry cough
  • Watery itchy eyes
  • Airway secretion clearance therapy
  • Expectorant


When to avoid taking Diphenhydramine? 

  • Allergic reactions
  • History of allergic reactions to similar medicines (Doctor consultation needed)


Popular Brand Names of Diphenhydramine

  • Acetadryl
  • Advil PM
  • Aleve PM
  • Allegra Cooling Relief Anti-itch
  • Banophen
  • Benadryl
  • Benadryl Itch Stopping
  • Benadryl-D Allergy and Sinus
  • Calagel
  • Damylin With Codeine
  • Dimetapp Nighttime Cold and Congestion 
  • Diphen
  • Diphenhist
  • Diphenist
  • Excedrin PM Triple Action
  • Goody's PM
  • Legatrin PM
  • Motrin PM
  • Nytol
  • Nytol Quickgels
  • Percogesic Reformulated Jan 2011 
  • Siladryl
  • Simply Sleep
  • Sleepinal
  • Sominex
  • Triaminic Night Time Cold and Cough
  • Tylenol PM
  • Unisom 
  • Unisom Sleep 
  • Vanamine 
  • Wal-dryl
  • Wal-som (doxylamine)
  • Z-sleep 
  • Zzzquil


Substitutes of Diphenhydramine

  • Amine 
  • Aromatic homomonocyclic compound 
  • Benzylether 
  • Dialkyl ether 
  • Diphenylmethane 
  • Ether 
  • Hydrocarbon derivative 
  • Organic nitrogen compound 
  • Organic oxygen compound 
  • Organonitrogen compound