Weefsel Pharma - Duloxetine Tablets Manufacturer and Exporter
Depression and anxiety attacks are two of the most common forms of mental disorders. With the recent social media buzz from various corners of the world, much of the taboos pertaining to mental illness have been fought out.
Weefsel Pharma has its own way of participation in this movement, i,e by manufacturing and exporting some of the most highly effective pharmaceutical drugs to cure depression and anxiety disorders. Duloxetine is one such antidepressant drug, similar to Dapoxetine and Fluoxetine.
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What is Duloxetine?
Having the brand name of Cymbalta among others, Duloxetine is an antidepressant medicine that is used to treat major depressive disorders, generalized anxiety disorder, fibromyalgia, and neuropathic pain. It has also been found useful against stressful urinary incontinence in women.
How does Duloxetine work?
Duloxetine is responsible for the reuptake of serotonin and norepinephrine in the central nervous system. It increases dopamine, specifically in the prefrontal cortex, where there are a couple of dopamine reuptake pumps, via reticence of norepinephrine reuptake pumps, which is believed to mediate the reuptake of dopamine and norepinephrine.
Duloxetine has no strong inclination for dopaminergic, cholinergic, histaminergic, opioid, glutamate, and GABA reuptake transporters, and can be categorised as a selective reuptake inhibitor at the 5-HT and NE transporters. This pharmaceutical drug undergoes extensive metabolism but is not significantly associated with pharmacologic activities.
Common Use or Treatments by Duloxetine
- Depressive disorder
- Anxiety disorder
- Diabetic Peripheral Neuropathy
- Fibromyalgia and chronic pain
- Urinary incontinence
- Chronic Musculoskeletal Pain
Usual Side effects of Duloxetine
- SSRI withdrawal symptoms
- Shortness of breath
- Nausea or Vomiting
- Constant headache
- Dizziness or Sleepiness
- Dry mouth
- Body pain
- Joint pain
- Abnormal ejaculation
- Loose stools or even constipation
- Shivers in hands or feet
- Painful erections that last longer than 4 hours (when not having sex)
- Decreased appetite and weight loss
- Hallucinations or aggression
- Feelings of euphoria, excessive enthusiasm or excitement, or even restlessness
- Bleeding gums, or bruises appearing without any reason or existing bruises getting bigger
- Sudden changes in periods, such as heavy bleeding, clotting or bleeding between periods
Compatibility with other medicines
- Aspirin- Medium
- Diuretics- Medium
- Ciprofloxacin- Severe
- Dextromethorphan- Severe
When to avoid Duloxetine?
- Allergic to duloxetine or any such other medicines
- Kidney problems
- Liver problems
- Heart problems
- Taking other medicines for depression within the last 14 days
- Fits, manic episodes or bipolar disorder
- Trying to get pregnant or already pregnant, or breastfeeding