Weefsel Pharma - Leading Linagliptin Manufacturer & Exporter in India 

According to World Health Organization (WHO), about 422 million people worldwide have diabetes, the majority living in low-and middle-income countries, and 1.5 million deaths are directly attributed to diabetes each year. The number is expected to reach about 643 million by 2030. Having said that, there are medications like Empagliflozin, Linagliptin, etc, that would help diabetic patients to cope with their symptoms. 

Products :

Product/Composition Strength View
Linagliptin and Metformin HCl Tablets 2.5mg + 1000mg, 2.5mg + 500mg, 2.5mg + 850mg View

What is Linagliptin?

Linagliptin is an FDA-approved antidiabetic pharmaceutical drug. This happens to be a dipeptidyl peptidase-4 (DPP-4) inhibitor used to manage hyperglycemia in patients with type 2 diabetes mellitus. In the simplest terms, Linagliptin is a medication only for type 2 diabetes and not type 1 diabetes. 

What are the uses of Linagliptin?: Medical Conditions Treated by Linagliptin 

As mentioned above, Linagliptin is an exclusive medication used to treat symptoms of only Type 2 Diabetes Mellitus. 

How does Linagliptin work?

As a dipeptidyl peptidase-4 (DPP-4) inhibitor, Linagliptin slows the breakdown of GLP-1 and glucose-dependant insulinotropic polypeptide (GIP). The GLP-1 and GIP stimulate the insulin release from beta cells in the pancreas while inhibiting the glucagon release from pancreatic beta cells. All these, together, reduce the breakdown of glycogen in the liver and increase insulin release in response to glucose; which is helpful in controlling type 2 diabetes in any patient. 

How long does Linagliptin take to come into action?

Usually, Linagliptin starts to work within a few hours. For example, a single 5 mg tablet may take 1.5 hours time to reach its peak. 

Dosage Forms Available for Linagliptin 

Common Dosage Strengths/ Powers of Linagliptin 

  • Linagliptin 5 mg 
  • Linagliptin 10 mg 
  • Linagliptin 500 mg 

Linagliptin Manufactured by Weefsel Pharma 

Linagliptin and Metformin HCl Tablets : 2.5mg + 1000mg, 2.5mg + 500mg, 2.5mg + 850mg

What is the storage temperature required for Linagliptin?

This medication can be stored at a room temperature range of 15°C to 30°C. However, it should be kept away from excess heat or even moisture. 

Popular Brand Names 

  • Glyxambi
  • Jentadueto
  • Tradjenta
  • Trajenta
  • Trijardy

Common Side Effects of Linagliptin Tablets

  • headache
  • joint pain
  • rash
  • itching, flaking, or peeling of the skin
  • hives
  • swelling of the face, lips, tongue, or throat
  • difficulty breathing or swallowing
  • hoarseness
  • ongoing pain that begins in the upper left or middle of the stomach but may spread to the back
  • nausea
  • vomiting
  • loss of appetite

Substituents of Linagliptin 

  • 3-aminopiperidine 
  • 6-oxopurine 
  • Alkaloid or derivatives 
  • Amine
  • Aminoimidazole
  • Aromatic heteropolycyclic compound  
  • Azacycle 
  • Azole 
  • Benzenoid 
  • Dialkylarylamine 
  • Diazanaphthalene 
  • Heteroaromatic compound 
  • Hydrocarbon derivative 
  • Imidazole 
  • Lactam 
  • N-substituted imidazole 
  • Organic nitrogen compound 
  • Organic oxide 
  • Organic oxygen compound 
  • Organonitrogen compound 
  • Organooxygen compound 
  • Organopnictogen compound 
  • Piperidine 
  • Primary aliphatic amine 
  • Primary amine 
  • Purinone 
  • Pyrimidine 
  • Pyrimidone 
  • Quinazoline 
  • Urea 
  • Vinylogous amide 
  • Xanthine