Weefsel Pharma - A Globally Leading Name for Manufacturing and Exporting Metformin in India 

As per the World Health Organization (WHO), about 422 million people worldwide have diabetes, and about 1.5 million deaths are directly happening due to diabetes every year. The number is expected to reach about 643 million by 2030. Having said that, there are medications like Empagliflozin, Linagliptin, Metformin, etc, that would help diabetic patients to cope with their symptoms.

Products :

Product/Composition Strength View
Metformin HCl Prolonged Release Tablets 1000mg, 500mg, 850mg View
Sitagliptin and Metformin Tablets 50mg + 1000mg, 50mg + 500mg View
Vildagliptin and Metformin HCl Tablets 50mg + 1000mg, 50mg + 500mg, 50mg + 850mg View
Empagliflozin and Metformin Tablets 12.5mg + 1000mg, 5mg + 500mg View
Linagliptin and Metformin HCl Tablets 2.5mg + 1000mg, 2.5mg + 500mg, 2.5mg + 850mg View
Metformin Tablets 1000mg, 250mg, 500mg, 750mg, 850mg View

What is Metformin?

Metformin is an FDA-approved antidiabetic pharmaceutical drug. It is a biguanide antihyperglycemic used in conjunction with diet and exercise for glycemic control in type 2 diabetes mellitus. 

It is also used off-label for insulin resistance in polycystic ovary syndrome (PCOS). 

What are the uses of Metformin?: Medical Conditions Treated by Metformin 

This medication is primarily used to treat symptoms of type 2 diabetes mellitus. However, it is also used off-label for insulin resistance in polycystic ovary syndrome (PCOS). 

Apart from that it is also associated with the treatment of cardiovascular problems, End Stage Renal Disease (ESRD), and decreased estimated glomerular filtration rate. 

How does Metformin work?

Metformin's mechanisms of action are unique from other classes of oral antihyperglycemic drugs. Metformin decreases blood glucose levels by decreasing hepatic glucose production (also called gluconeogenesis), decreasing the intestinal absorption of glucose, and increasing insulin sensitivity by increasing peripheral glucose uptake and utilization. 

How long does Metformin take to show full results?

Metformin may start to work within the first week of treatment. But it takes about 2 months for it to have its full glucose-lowering effect.

Dosage Forms Available for Metformin 

Common Dosage Strengths/ Powers of Metformin 

  • Metformin 500 mg 
  • Metformin 750 mg 
  • Metformin 850 mg
  • Metformin 1000 mg 

Metformin is Manufactured by Weefsel Pharma 

What is the storage temperature required for Metformin?

This medication can be stored at room temperature between 15 and 30 degrees Celsius (59 and 86 degrees F). But it has to be kept away from moisture, heat, and light.

Popular Brand Names 

  • Actoplus Met
  • Avandamet
  • Fortamet
  • Glucophage
  • Glucovance
  • Glumetza
  • Glycon
  • Invokamet
  • Janumet
  • Jentadueto
  • Kazano
  • Kombiglyze
  • Komboglyze
  • Qternmet
  • Riomet
  • Segluromet
  • Synjardy
  • Trijardy
  • Velmetia
  • Xigduo

Common Side Effects of Metformin 

  • diarrhea
  • bloating
  • stomach pain
  • gas
  • indigestion
  • constipation
  • unpleasant metallic taste in the mouth
  • heartburn
  • headache
  • flushing of the skin
  • nail changes
  • muscle pain
  • Chest pain 
  • Rash

Substituents of Metformin 

  • Aliphatic acyclic compound 
  • Biguanide 
  • Carboximidamide 
  • Hydrocarbon derivative 
  • Imine 
  • Organic 1,3-dipolar compound 
  • Organopnictogen compound 
  • Propargyl-type 1,3-dipolar organic compound