Weefsel Pharma - Globally Leading Pantoprazole Capsules Manufacturer and Exporter in India 

Being a globally leading pharma manufacturing and exporting firm from India, we at Weefsel Pharma, carry tremendous responsibility for providing our customers with core and allied healthcare products that speak for themselves, projecting the finest possible quality, and that too coming from multiple categories. We take extreme pride to have been able to create a stable and ever increasing market, across more than fifty nations, for our products and services

The wide range of pharma products that we are maintaining with these countries include a wide range of both branded as well as generic medicines. Of these medicines, Pantoprazole is a drug that has generated much demand. We as a globally reputed, Pantoprazole manufacturer and exporter in India, are maintaining world-class standards in each of our production units.

 

Combinations of Pantoprazole Manufactured by Weefsel Pharma

  • Pantoprazole + Domperidone
  • Pantoprazole IP + Domperidone IP

Products :

Product/Composition Strength View
Pantoprazole and Domperidone Tablets 40mg + 10mg, 40mg + 30mg View
Domsel P Tablets 40mg + 10mg View
Pantoprazole and Domperidone Capsules 40mg + 30mg View
Pantoprazole Injection 40mg View
Pantoprazole Tablets 20mg, 40mg View

What is Pantoprazole?   

Pantoprazole is a first-generation proton pump inhibitor used to treat erosive esophagitis, gastric acid hypersecretion, and to promote healing of tissue damage caused by gastric acid. It is available as a generic medication. The inhibition of gastric acid secretion is stronger in case of the proton pump inhibitors like pantoprazole, and lasts for much longer duration than with the H(2) antagonists. Pantoprazole happens to be a substituted benzimidazole derivative and a weak base by nature. 

 

How does Pantoprazole work? 

Hydrochloric acid (HCl) secretion into the gastric lumen is a process regulated mainly by the H(+)/K(+)-ATPase of the proton pump, which happens in high quantities by the parietal cells of the stomach. Now, the ATPase is an enzyme on the parietal cell membrane that facilitates the exchange of hydrogen and potassium through the cell, that generally results in the extrusion of potassium and formation of the gastric acid i,e HCl. 

What Pantoprazole does is that it accumulates in the acidic space of the parietal cell before being converted in the canaliculi or small canal of the gastric parietal cell, an acidic environment, in order to activate the sulfenamide derivatives. From here, the active form makes certain disulfide bonds with the important cysteines on the gastric acid pump, inhibiting its function. Further, pantoprazole is supposed to bind on to the sulfhydryl group of H+, K+-ATPase, which is an enzyme implicated in accelerating the final step in the acid secretion pathway. Eventually, at the end the enzyme is inactivated, thereby inhibiting the gastric acid secretion.

 

When to avoid taking Pantoprazole

  • Bone fractures 
  • Gut infections 
  • Vitamin B12 deficiency 
  • Pregnant (consult doctor) 
  • Breast feeding 
  • Old age (consult doctor) 

 

Popular Diseases or Health Issues treated by Pantoprazole 

  • Erosive Esophagitis
  • GERD With Erosive Esophagitis
  • Gastro-esophageal Reflux Disease (GERD)
  • Healing
  • Heartburn
  • Helicobacter Pylori Infection
  • Stress Ulcers
  • Zollinger-Ellison Syndrome
  • Need of lowering down excess gastric acid secretion 
  • Pathological hypersecretory conditions

 

Dosage forms of Pantoprazole Manufactured by Weefsel Pharma 

 

Popular Brand Names of Pantoprazole 

  • Protonix 
  • Somac Control 
  • Tecta

 

Substitutes of Pantoprazole 

  • Alkyl aryl ether  
  • Alkyl fluoride  
  • Alkyl halide  
  • Aromatic heteropolycyclic compound  
  • Azacycle  
  • Azole 
  • Benzenoid  
  • Ether 
  • Heteroaromatic compound 
  • Hydrocarbon derivative  
  • Imidazole 
  • Organic nitrogen compound 
  • Organic oxide  
  • Organic oxygen compound 
  • Organofluoride  
  • Organohalogen compound  
  • Organonitrogen compound  
  • Organooxygen compound  
  • Organopnictogen compound  
  • Organosulfur compound  
  • Pyridine  
  • Sulfinyl compound  
  • Sulfinylbenzimidazole 
  • Sulfoxide