Weefsel Pharma - A Top Rated Sitagliptin Tablets Manufacturer and Exporter in India  

If WHO (World Health Organization) is to be believed, about 1.5 million deaths are directly related to diabetes every year, and the total number of people affected by diabetes is expected to reach about 643 million by 2030. Having said that, there are medications like Linagliptin, Metformin, Sitagliptin, etc, that would help diabetic patients to cope with their symptoms. Let us check some important information about Sitagliptin. 

Products :

Product/Composition Strength View
Sitagliptin and Metformin Tablets 50mg + 1000mg, 50mg + 500mg View
Sitagliptin Tablets 100mg, 25mg, 50mg View

What is Sitagliptin?

Sitagliptin is an FDA-approved antidiabetic medication. It belongs to the class of pharmaceutical compounds called dipeptidyl peptidase-4 (DPP-4) inhibitors. 

This medication is often prescribed for lowering blood sugar levels in patients with type 2 diabetes; a condition in which blood sugar is too high because the body does not produce or use insulin normally. 

It works by increasing the amounts of certain natural substances that lower blood sugar when it is high. Just like Linagliptin, Sitagliptin also is barred from treating type 1 diabetes.


What are the uses of Sitagliptin?: Medical Conditions Treated by Sitagliptin 

This is an exclusive medication for treating symptoms of only Type 2 Diabetes Mellitus. 


How does Sitagliptin work?

It works by increasing the amounts of certain natural substances that lower blood sugar when it is high. Being inhibited by Sitagliptin DPP-4 slows the inactivation of incretins like GLP-1 and GIP. Reduced inhibition of incretins increases insulin synthesis and decreases glucagon release in a manner dependent on glucose concentrations. 


How long does Sitagliptin take to show full results? 

The blood sugar level tends to be in control after one to two weeks of treatment under Sitagliptin. 


Dosage Forms Available for Sitagliptin 


Common Dosage Strengths/ Powers of Sitagliptin 

  • Sitagliptin 5 mg
  • Sitagliptin 10 mg 
  • Sitagliptin 25 mg 
  • Sitagliptin 50 mg 
  • Sitagliptin 100 mg 
  • Sitagliptin 500 mg 


Sitagliptin Manufactured by Weefsel Pharma 


What is the storage temperature required for Sitagliptin?

This medication can be stored at a room temperature range of 15°C to 30°C. However, it should be kept away from excess heat or even moisture. 


Popular Brand Names 

  • Janumet
  • Januvia 
  • Ristaben
  • Steglujan
  • Tesavel
  • Velmetia
  • Xelevia


Common Side Effects of Sitagliptin 

  • stuffed or runny nose
  • sore throat
  • headache
  • diarrhea
  • nausea
  • fever, 
  • nausea, 
  • vomiting, 
  • loss of appetite, 
  • Stomach ache that spreads till the back 
  • shortness of breath, rapid weight gain, or swelling of feet or ankles
  • itchy skin, skin blistering or peeling
  • joint pain
  • rash
  • hives
  • swelling of the face, lips, tongue, and throat
  • difficulty in breathing or swallowing


Substituents of Sitagliptin 

  • 1,2,4-triazole 
  • Alkyl fluoride
  • Alkyl halide 
  • Amine 
  • Amphetamine or derivatives 
  • Aralkylamine 
  • Aromatic heteropolycyclic compound 
  • Aryl fluoride
  • Aryl halide 
  • Azacycle
  • Azole 
  • Benzenoid 
  • Beta amino acid or derivatives 
  • Carbonyl group
  • Carboxamide group 
  • Fluorobenzene 
  • Halobenzene 
  • Heteroaromatic compound 
  • Hydrocarbon derivative 
  • Monocyclic benzene moiety
  • Organic nitrogen compound 
  • Organic oxide 
  • Organic oxygen compound
  • Organofluoride 
  • Organohalogen compound 
  • Organoheterocyclic compound 
  • Organonitrogen compound 
  • Organooxygen compound
  • Organopnictogen compound
  • Primary aliphatic amine 
  • Primary amine 
  • Pyrazine 
  • Tertiary carboxylic acid amide 
  • Triazole 
  • Triazolopyrazine