Weefsel Pharma - A Prominent Thiocolchicoside Manufacturer and Exporter in India 

As an eminent and globally acclaimed pharmaceutical manufacturing and exporting company, we at Weefsel Pharma, are known to offer a well-maintained inventory of pain management medications or painkillers, which happens to include only the top-rated neuropathic pain medicines, to be delivered at any point in time, to any part of the world. 

When we talk about painkillers, medicines like Acetaminophen, Serratiopeptidase, and Thiocolchicoside, are a few of the most globally demanded pharmaceutical drugs. Let us go through some of the most important aspects of Thiocolchicoside over here.  

What is Thiocolchicoside?

Thiocolchicoside is a synthetic sulfur derivative of colchicoside, a naturally occurring glucoside contained in the Colchicum autumnale plant. It is used as an analgesic and also as an anti-inflammatory pharmaceutical drug.

What are the uses of Thiocolchicoside? : Diseases or Health Issues treated by Thiocolchicoside 

This FDA-approved pharmaceutical drug can be used to treat the following medical conditions: 

  • Back Pain 
  • Chronic Back Pain
  • Extra-Articular Rheumatism
  • Muscle Inflammation
  • Muscle Spasms
  • Musculoskeletal Pain
  • Myalgia
  • Nonspecific Pain Post-Traumatic Injury
  • Osteoarthritis (OA)
  • Pain
  • Post Traumatic Pain
  • Postoperative pain
  • Rheumatoid Arthritis
  • Spasms
  • Spinal pain
  • Vertebral column pain
  • Inflammation localized
  • Localized pain
  • Mild to moderate pain
  • Musculoskeletal spasms

How does Thiocolchicoside work?

Thiocolchicoside has a selective and potent affinity for g-aminobutyric acid A (GABA-A) receptors and acts on muscular contractures by activating the GABA inhibitory pathways thereby behaving as a potent muscle relaxant.

GABAergic neurons are involved in myorelaxation, anxiolytic treatment, sedation, and anesthetics. They can also modulate heart rate and blood pressure.

How long does Thiocolchicoside take to come into action?

Post intramuscular administration, this medication reaches its climax in about 30 minutes. 

Common Dosage Strengths/Powers of Thiocolchicoside 

  • Thiocolchicoside 2 mg / ml 
  • Thiocolchicoside 4 mg 
  • Thiocolchicoside 8 mg 
  • Thiocolchicoside 90 mg

Thiocolchicoside Dosage Forms Manufactured by Weefsel Pharma 

Thiocolchicoside Manufactured by Weefsel Pharma 

Popular Brand Names of Thiocolchicoside 

  • Muscoril
  • Myoril
  • Neoflax

How to store Thiocolchicoside?

This medication should be stored in an airtight container and in a well-ventilated room with a temperature range of 2°C to 8°C (35.6 °F to 46.4 °F). It is a heat-sensitive drug that should be kept away from heat and moisture as well. 

Common Side Effects of Thiocolchicoside 

  • Itching and skin rash
  • Swelling of face, lips, eyelids, tongue, hands and feet 
  • Fainting and drowsiness
  • Nausea and Vomiting
  • Diarrohea
  • Yellowing of skin and eyes
  • Photosensitivity
  • Dry mouth
  • Headache
  • Stomach pain

Thiocolchicoside and Adverse Interactions with Other Drugs 

  • CNS depressants
  • Other muscle relaxants

Substituents of Thiocolchicoside 

  • Acetal
  • Acetamide
  • Alcohol
  • Alkyl aryl ether
  • Alkylarylthioether
  • Anisole
  • Aromatic heteropolycyclic compound
  • Aryl thioether 
  • Benzenoid
  • Carbonyl group
  • Carboxamide group
  • Carboxylic acid derivative
  • Cyclic ketone
  • Ether
  • Hexose monosaccharide
  • Hydrocarbon derivative
  • Monosaccharide
  • O-glycosyl compound
  • Organic nitrogen compound
  • Organic oxide
  • Organoheterocyclic compound
  • Organonitrogen compound
  • Organopnictogen compound
  • Organosulfur compound
  • Oxacycle
  • Oxane
  • Phenolic glycoside
  • Polyol
  • Primary alcohol
  • Secondary alcohol
  • Secondary carboxylic acid amide
  • Sulfenyl compound
  • Thioether
  • Tropone