Weefsel Pharma - A Globally Esteemed and Acclaimed Tolnaftate Cream Manufacturer and Exporter in India 

As a responsible and trustworthy pharmaceutical company, we at Weefsel Pharma, move towards the ultimate goal of providing the world with a vast range of core and allied healthcare products that showcases only the finest possible quality; coming from multiple categories. It is just an added bonus for us that while moving towards this goal, we have successfully generated record high sales in this highly competitive world of pharmaceuticals. We take extreme pride to have been able to create a stable and constantly increasing market, across more than fifty countries, for our products and services

The portfolio that we are currently maintaining, include a wide range of pharma products. We are proudly delivering these to numerous countries across the globe. It should be noted here that we have included both branded as well as generic medicines in our product portfolio, having exclusive segments for both human healthcare as well as veterinary medicines. 

Among the medicines that we export worldwide, Tolnaftate happens to be a pharmaceutical drug that has seen much significant demand. Being a globally reputed Tolnaftate manufacturer and exporter based out of India, we at Weefsel Pharma are maintaining the best of world-class standards in each of our production units.


Combinations of Tolnaftate Manufactured by Weefsel Pharma 

  • Ketoconazole + Neomycin + Tolnaftate + Iodochlorhydroxyquinoline + Clobetasol Propionate
  • Ketoconazole IP + Neomycin IP + Tolnaftate IP + Iodochlorhydroxyquinoline IP + Clobetasol Propionate IP


Dosage forms of Tolnaftate Manufactured by Weefsel Pharma 

Products :

Product/Composition Strength View
Ketoconazole, Neomycin, Tolnaftate, Iodochlorhydroxyquinoline and Clobetasol Propionate Cream 2% w/w + 0.1% w/w + 1% w/w + 1% w/w + 0.05% w/w View
Ketosel CT Cream 2% w/w + 0.1% w/w + 1% w/w + 1% w/w + 0.05% w/w View

What is Tolnaftate?   

Tolnaftate is a synthetic thiocarbamate used as an antifungal agent used to treat various skin infections caused by fungi, and can also be taken in combination with some other anti-fungal medicines. 

Tolnaftate is a thiocarbamate derivative with either fungicidal or fungistatic property. 

This pharmaceutical drug has been found to be slightly less effective than azoles when used to treat tinea pedis or athlete's foot. However, it has been found useful while dealing with ringworm, especially when passed from pets to humans. 


How does Tolnaftate work? 

Tolnaftate is a topical fungicide. Although its exact mechanism of action is yet unknown, it is believed to inhibit squalene epoxidase, an important enzyme in the biosynthetic pathway of ergosterol which is a key component of the fungal cell membrane, in a similar way to terbinafine. 

Chemically speaking, it is a selective, reversible and non-competitive inhibitor of membrane-bound squalene-2,3- epoxidase, an enzyme involved in the biosynthesis of ergosterol. This inhibition culminates into the accumulation of squalene and a deficiency in ergosterol, an essential component of fungal cell walls, which eventually increases the membrane permeability, disrupting cellular organization and causing cell death. Additionally, this agent may also distort the hyphae and stunts mycelial growth in susceptible fungi. 

In simple terms, it is supposed to prevent ergosterol biosynthesis by inhibiting squalene epoxidase. It has also been reported to distort the hyphae and to stunt mycelial growth in susceptible organisms. 


Popular Treatments or Diseases and Health Issues associated with Tolnaftate  

  • Athlete's foot or tinea pedis
  • Dermatophytosis
  • Jock itch
  • Pityriasis versicolor
  • Ringworm
  • Tinea Corporis
  • Tinea Cruris


When to avoid taking Tolnaftate? 

  • Allergic reactions
  • History of allergic reactions to similar medicines 


Popular Brand Names of Tolnaftate 

  • Absorbine Jr Antifungal 
  • Clarus 
  • Fungi-nail 
  • Fungoid-D 
  • Sanafitil Antifungal 
  • Silka Cream 
  • Tinactin 
  • Tineacide Antifungal 
  • Ting
  • Aftate
  • Blis-To-Sol
  • Dermasept Antifungal
  • Fungi-Guard
  • Podactin
  • Q-Naftate
  • Tinaderm
  • Athletes Foot Gel
  • Dr Scholls Athletes Foot
  • Pitrex
  • Scholls Athletes Foot Spray
  • Scholl Tritin Antifungal Powder
  • Scholl Tritin Antifungal Spray Powder
  • Tinactin Aerosol Liquid
  • Tinactin Aerosol Powder
  • Tinactin Jock Itch
  • Tinactin Plus
  • Tinactin Plus Aerosol Powder


Substitutes of Tolnaftate 

  • Aromatic homopolycyclic compound 
  • Hydrocarbon derivative 
  • Monocyclic benzene moiety 
  • Naphthalene 
  • Organic nitrogen compound 
  • Organic oxygen compound 
  • Organonitrogen compound  
  • Organooxygen compound  
  • Organopnictogen compound 
  • Organosulfur compound